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Aunque estos estudios estn publicados en revistas indexadas, la replicacin independiente por parte de otros grupos de investigacin sigue siendo insuficiente para extraer conclusiones definitivas sobre la eficacia teraputica en humanos

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This modification leads to the remodeling of chromatin structure and the recruitment of DNA repair proteins, such as X-ray repair cross-complementing protein 1 (XRCC1), DNA ligases, and DNA polymerases (129, 130)