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glabrata showed 14.3% resistance to fluconazole and 11.6% cross-resistance to voriconazole (Xiao et al., 2015)

Low BDNF in the hippocampus and amygdala is associated with increased anxiety-like behavior in animal models, and human studies show reduced serum BDNF in patients with generalized anxiety disorder

These findings suggest that Tet2 is a transcriptional gene associated with macrophage NLRP3 inflammasomes and promoting its overexpression in macrophages could serve as a potential therapeutic approach to mitigate the inflammatory response in HUA (34)

Both in vivo and in vitro studies show ASTs ability to enhance cognitive function, reduce neuroinflammation, and modulate key neurodegenerative pathways