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And it is encouraging news for some 40 million Americans who have low bone density, a warning sign that osteoporosis is developing behind the scenes

To mitigate these adverse effects, researchers have developed NAV-Gal, a prodrug of Navitoclax that is selectively activated by senescence-associated -galactosidase (SA--Gal) within senescent cells, thereby reducing off-target toxicity in non-senescent cells (Paez-Ribes et al., 2019)