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Hebert et al., 2007), its findings heavily influenced future treatment guidelines, promoting the use of thiazide diuretics (Chobanian et al., 2003

Therefore, the newly synthesized NRF2 accumulates in the cell, enabling it to exert its antioxidant and cellular protective functions [26]

Dilda, Tumour Metabolism Group, Adult Cancer Program, Lowy Cancer Research Centre and Prince of Wales Clinical School, Faculty of Medicine, University of New South Wales, Sydney, NSW 2052, Australia e-mail: [email protected] This article was submitted to Experimental Pharmacology and Drug Discovery, a section of the journal Frontiers in Pharmacology

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