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Senescent cells stop multiplying, but they dont die off when they should, which can lead to more inflammation and accelerated aging

By inhibiting the JAK/STAT pathway, these agents simultaneously block multiple cytokine-driven inflammatory pathways, reducing the transcription of pro-inflammatory cytokines, thereby effectively alleviating inflammation while potentially mitigating adverse effects (118)

For most users, noticeable improvements appear gradually over weeks of consistent use, though individual results can vary

CJC-1295 (No DAC) is a GHRH analogue that stimulates growth hormone release via the GHRH receptor, while Ipamorelin is a selective GH secretagogue acting through the ghrelin receptor with minimal cortisol or prolactin response