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Key Takeaway: Glutathione is a self-produced antioxidant concentrated in the liver that serves as the bodys primary defense against oxidative stress and cellular damage

Example: One patient from Arizona came to us because, despite being maximized on treatment for Rheumatoid arthritis with DMARDs and a biologic, her disease control was very poor

Conclusions These results demonstrate that gene-expression changes associated with regional emphysema severity within an individual's lung can provide insights into emphysema pathogenesis and identify novel therapeutic opportunities for this deadly disease

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