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Adequate levels of glutathione are essential in our mitochondria , where reactive oxygen species (ROS) are constantly being formed as a minor by-product of oxidative respiration (and in response to some drugs or metabolites that interfere with mitochondrial respiration)

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W osoczu mlodych doroslych mierzy sie okolo 200 ng/mL (okolo 10^-7 M), a do szostej dekady zycia wartosc ta spada do okolo 80 ng/mL (Pickart i in., 2015)