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Clearly the thymic selection process is imperfect, in a developmental process designed to provide the maximum repertoire of lymphocytes, some lymphocytes which weakly recognize autologous thyroid antigens do persist in the circulation, and can be found in normal patients and those with AITD (Table 1) (85)

DMSO only in matching concentrations (0.1-1%) was used as the vehicle control

The antifungal agent ketoconazole has a dual role in hair loss compounding: it reduces Malassezia overgrowth on the scalp (a contributor to follicular inflammation and seborrheic dermatitis) and has demonstrated weak anti-androgenic properties

If pain is not tolerable, you can use over-the-counter pain relief like paracetamol