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Rev Infect Dis

Starting too early could theoretically interfere with the natural healing cascade, though preclinical data generally suggests BPC-157 supports rather than disrupts normal healing processes

Eligibility Criteria Studies were eligible if they evaluated BPC-157, thymosin beta-4 or marketed derivatives (including TB-500), GHK-Cu, or other peptide-based agents commonly promoted for musculoskeletal healing or recovery and reported outcomes relevant to musculoskeletal pathology, orthopaedic surgery, postoperative recovery, or perioperative risk domains

BPC-157: Multi-mechanism regenerative effects Tendon and ligament healing: Most robust research exists for BPC-157 tendon repair