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Medical conditions associated with lower testosterone levels Type 2 diabetes Metabolic syndrome Chronic kidney disease Liver disease HIV/AIDS Chronic inflammatory conditions Mumps Trauma to the testes Medications and Low Testosterone There are several medications used regularly by middle-aged men which can potentially lower testosterone levels, including: Statins (cholesterol-lowering drugs) some evidence suggests modest testosterone reduction Antidepressants (particularly SSRIs) can affect sexual function and may influence testosterone Blood pressure medications (especially beta-blockers and spironolactone) some types more than others Opioid painkillers (including prescription pain medications) can significantly suppress testosterone, sometimes causing opioid-induced hypogonadism Antiepileptic drugs (certain seizure medications) Antipsychotic medications (especially those affecting prolactin levels) Corticosteroids (long-term use) Finasteride (Post-Finasteride Syndrome PFS) Dr Ed says: detective work in the clinic When I see patients in my clinic, Im acting like a detective to work out if they have low testosterone, and more importantly, why

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