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The blend typically consists of Virginia (flue-cured), Burley (air-cured), and Oriental (sun-cured) tobaccos

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PentelPRKeylerDEChenYLeSageMGDufekMBLeCet alVaccination against nicotine does not prevent nicotine-induced changes in fetal nicotinic receptor binding and c-fos mRNA expression in rats

It's a direct result of this repeated genetic damage from carcinogens