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In breast cancer, recurrence following primary breast cancer can be local (in the same place), regional (in surrounding tissue) or metastatic (in some other part of the body)., increases breast cancer mortality and is linked to poor prognosisThe expected or likely outcome of a disease, usually based on a statistical analysis of large groups of patients

[8] Some studies show that menthol acts as a GABA A receptor positive allosteric modulator and increases GABAergic transmission in PAG neurons

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