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Yeongkwon Son, Chiranjivi Bhattarai, Vera Samburova, Andrey Khlystov Int J Environ Res Public Health Dangerous levels of harmful chemicals in electronic cigarette (e-cigarette) aerosols were reported by several studies, but variability in e-cigarette design and use patterns, and a rapid development of new devices, such as JUUL, hamper efforts to develop standardized testing protocols and understand health risks associated with e-cigarette use