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Often, they also contain carcinogens, such as tobacco-specific nitrosamines (TSNA), arsenic, beryllium, cadmium, nickel, chromium, nitrite and nitrate, in varying levels depending on the product [5, 6]

The fact that the number of P/S cells expressing CK5+, CK14+ and p63+ were decreased in our BEC population with advancing outgrowth numbers, it is tempting to speculate that this might also be due to a dysfunction in the YAP/TAZ signaling pathway during this process