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These challenges include degradation by cellular nucleases, high renal clearance, and low penetration in biological membranes due to their negative charge

Age Age is a risk factor for drug-induced hepatotoxicity from specific medications.3 Younger age is a risk factor for particular medications such as valproic acid and aspirin.74 In contrast, older ages might be more susceptible to some other medications such as isoniazid,75 amoxicillin/clavulanate,76 erythromycin,3 and many other drugs

These findings position Rh2-O as a candidate for liver cancer therapy and 2-Deoxy-Rh2 for breast cancer treatment (100, 101)

Choosing clinics that provide comprehensive follow-up care to monitor progress after treatment is crucial